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Roche NimbleGen, Caliper Partner to Automate Target Enrichment


Roche NimbleGen and Caliper Life Sciences plan to develop and optimize protocols for the use of NimbleGen's target capture method with Caliper's liquid-handling system, the companies said this week.

Under the co-marketing agreement, the companies will develop automated methods for sequencing library preparation, enrichment of target regions, quantification, and quality control using NimbleGen's SeqCap EZ Library solution-based capture method and Caliper's Sciclone NGS Workstation.

Caliper already has a number of partnerships with other firms to automate aspects of next-generation sequencing sample prep using its equipment, for example with NuGen Technologies (IS 2/1/2011), Covaris (IS 3/1/2011), and EdgeBio (IS 6/28/2011).

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.