Scientists at Roche Molecular Systems have been exploring using the 454 Life Sciences GS FLX for high-resolution HLA DNA typing in research, an application that 454 said it believes could become one of the first clinical applications of the platform.

454 says that some of its customers outside the US are close to using the 454 platform for clinical HLA typing. In addition, the company is working with the FDA to find ways to provide the system to US testing labs, some of which doubt that the platform has become robust and cheap enough for such use.

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