Researchers Propose Sequencing-Based Approach to Map all Neuron Connections in the Brain | GenomeWeb

Researchers at Cold Spring Harbor Laboratory are proposing to use high-throughput sequencing to draw a wiring diagram of all neurons in the brain at approximately the cost of sequencing a human genome.

In an article published in PLoS Biology last week, the team, led by Tony Zador, a professor of neurobiology at CSLH, outlined their approach, called BOINC for barcoding of individual neuronal connections, in which sequencing serves as the final readout step.

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