By Monica Heger

Adding to the debate on the importance of non-coding sequences to disease, two separate groups recently used sequencing to identify a repeat expansion in a non-coding region of chromosome 9 as the most common genetic cause of both familial amyotrophic lateral sclerosis and frontal temporal dementia.

The two groups, one led by the National Institutes of Health and the other by the Mayo Clinic Florida, published their results in a recent issue of Neuron.

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