Skip to main content
Premium Trial:

Request an Annual Quote

Regeneron, Scandanavian Schools to Study Genetics of Diabetes

NEW YORK (GenomeWeb) – Lund University said last week that it has partnered with the Regeneron Genetics Center (RGC) and the University of Helsinki on a study to investigate the genetics of diabetes.

In the so-called Botnia study, the RCG — a subsidiary of Regeneron Pharmaceuticals — will perform exome sequencing and whole-genome array genotyping of more than 9,000 individuals with diabetes or with diabetic relatives from around 1,400 families in Finland and southern Sweden.

Researchers from the RCG, Lund University, and the University of Helsinki will analyze the data in order to identify genetic mutations linked to different conditions associated with diabetes such as insulin sensitivity. 

"By studying hereditarily transmitted mutations in families, we can understand which causes are genetic and which are environmental, i.e. due to lifestyle," Leif Groop, head of the Lund University Diabetes Centre, said in a statement.

"If we can understand the cause, we can study the molecular mechanism behind the disease, which would enable the development of new drugs to treat it," Nikolay Oskolkov, a researcher at the center, added.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.