Rare Variant Studies Underscore Immune Pathway Role in Age-related Macular Degeneration | GenomeWeb

NEW YORK (GenomeWeb News) – A trio of studies published online yesterday in Nature Genetics are revealing new, rare risk loci for age-related macular degeneration.

For the first of these, researchers from the University of Michigan, Washington University, the National Institutes of Health's National Eye Institute, and elsewhere did targeted sequencing on 2,335 individuals with AMD and nearly 800 unaffected controls, focusing on 10 suspicious sites in the genome.

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