By Andrea Anderson

NEW YORK (GenomeWeb News) – By sequencing the protein-coding repertoire or expressed RNA transcripts from more than a dozen rare ovarian tumors, a Canadian team has uncovered recurrent mutations in the microRNA-processing gene DICER1 — changes also found in a subset of other tumors involving primitive tissue types.

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In PNAS this week: co-evolutionary signatures of insect hosts and bacterial symbionts, distinct transcript isoforms of high-grade ovarian cancer, and more.

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