A team from the US and Singapore has come up with a method for nearly doubling Illumina read lengths using overlapping libraries, producing reads that approach the 500 base pair mark.

The strategy relies on the production of "contiguous" reads from two shorter sequences that overlap by a few dozen bases, in some experiments, or by just a handful of bases in the case of the most well-characterized samples, explained Stephan Schuster, a researcher affiliated with Pennsylvania State University and Singapore's Nanyang Technological University.

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In Science this week: self-assembly of DNA components in solution, and more.

Genetics and Molecular Research retracts two gastric cancer papers for being "substantially equal" to other papers, according to Retraction Watch.

A new analysis indicates that the Ebola virus behind the current West African outbreak is mutating at about the same rate as other Ebola viruses.

With the launch of Scott Kelly into space today, the study of him and his earthbound brother to disentangle the effects of life in space from the effects of genetics kicks off.

Apr
15
Sponsored by
WaferGen

This live online seminar will highlight recent trends in applying next-generation sequencing in the clinical setting, with a particular focus on oncology and rare disease.