CHICAGO (GenomeWeb) – A team led by the Institute of Cancer Research in the UK has used exome sequencing in an effort to tease out prostate cancer molecular features that are associated with a response to the checkpoint blockade immunotherapy drug pembrolizumab (Merck's Keytruda).

At the American Society of Clinical Oncology meeting here this week, Johann de Bono, director of the ICR's drug development unit, shared data from the Keynote-199 study, a Phase II trial comparing pembrolizumab response in 258 metastatic prostate cancer cases with or without tumor expression of PD-L1.

To read the full story....

Register for Free.

...and receive Daily News bulletins.

Already have a GenomeWeb or 360Dx account?
Login Now.

The Washington Post reports on a Federal Bureau of Investigation plan to place rapid DNA analyzers at booking stations around the country.

In an editorial, officials from scientific societies in the US and China call for the international community to develop criteria and standards for human germline editing.

The US National Institutes of Health is to review studies that have received private support for conflicts of interest, according to the New York Times.

In Science this week: the PsychENCODE Consortium reports on the molecular mechanisms of neuropsychiatric disorders, and more.

Jan
30
Sponsored by
Loop Genomics

This webinar will provide a comparison of several next-generation sequencing (NGS) approaches — including short-read 16S, whole-genome sequencing (WGS), and synthetic long-read sequencing technology — for use in microbiome research studies.

Jan
30
Sponsored by
Loop Genomics

This webinar will provide a comparison of several next-generation sequencing (NGS) approaches — including short-read 16S, whole-genome sequencing (WGS), and synthetic long-read sequencing technology — for use in microbiome research studies.

Jan
31
Sponsored by
Roche

This webinar highlights the use of single-cell genomics to identify distinct cell types and states associated with enhanced immunity.