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In Print: Last Week's Clinical Sequencing Papers of Note: Dec 12, 2012


Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from The Children's Oncology Group TARGET Project.
Loh ML, Zhang J, Harvey RC, Roberts K, et al.
Blood. 2012 Dec 4. [Epub ahead of print]

CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
McNerney ME, Brown CD, Wang X, Bartom ET, et al.
Blood.2012 Dec 3. [Epub ahead of print]

Symptomatic atherosclerosis is associated with an altered gut metagenome.
Karlsson FH, Fåk F, Nookaew I, Tremaroli V, et al.
Nat Commun.2012 Dec 4;3:1245.

Deep-intronic ATM mutation detected by genomic resequencing and corrected in vitro by antisense morpholino oligonucleotide (AMO).
Cavalieri S, Pozzi E, Gatti RA, Brusco A.
Eur J Hum Genet. 2012 Dec 5. [Epub ahead of print]

DNAJC6 is responsible for juvenile Parkinsonism with phenotypic variability.
Köroğlu C, Baysal L, Cetinkaya M, Karasoy H, Tolun A.
Parkinsonism Relat Disord.2012 Dec 1. [Epub ahead of print]

An alpha-E-catenin (CTNNA1) mutation in hereditary diffuse gastric cancer.
Majewski IJ, Kluijt I, Cats A, Scerri TS, et al.
J Pathol. 2012 Dec 3. [Epub ahead of print]

A sensitive and specific diagnostic test for hearing loss using a microdroplet PCR-based approach and next generation sequencing.
Schrauwen I, Sommen M, Corneveaux JJ, Reiman RA, et al.
Am J Med Genet A. 2012 Dec 3. [Epub ahead of print]

Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion.
Adhikary T, Brandt DT, Kaddatz K, Stockert J, et al.
Oncogene. 2012 Dec 3. [Epub ahead of print]

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