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In Print: Last Week's Clinical Sequencing Papers of Note: Nov 9, 2011


Nonhematopoietically derived DNA is shorter than hematopoietically derived DNA in plasma: a transplantation model.
Zheng YW, Chan KC, Sun H, Jiang P, et al.
Clin Chem. 2011 Nov 3. [Epub ahead of print]

RNA-seq analyses generate comprehensive transcriptomic landscape and reveal complex transcript patterns in hepatocellular carcinoma.
Huang Q, Lin B, Liu H, Ma X, et al.
PLoS One. 2011;6(10):e26168.

Next-generation sequencing reveals regional differences of the α-synuclein methylation state independent of Lewy body disease.
de Boni L, Tierling S, Roeber S, Walter J, et al.
Neuromolecular Med. 2011 Nov 1. [Epub ahead of print]

Assessing diversity of the female urine microbiota by high throughput sequencing of 16S rDNA amplicons.
Siddiqui H, Nederbragt AJ, Lagesen K, Jeansson SL, Jakobsen KS.
BMC Microbiol. 2011 Nov 2;11(1):244. [Epub ahead of print]

Rep-Seq: uncovering the immunological repertoire through next generation sequencing.
Benichou J, Ben-Hamo R, Louzoun Y, Efroni S.
Immunology. 2011 Oct 27. [Epub ahead of print]

Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes.
Brown CT, Davis-Richardson AG, Giongo A, Gano KA, et al.
PLoS One. 2011;6(10):e25792.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.