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NEW YORK – Seemingly normal skin samples may contain cutaneous melanoma-related mutations that may be missed by focusing on risky-looking naevi, or moles, according to a new study focused on ultraviolet light-linked DNA damage patterns.

"It turns out that a multitude of individual cells in so-called normal skin are riddled with mutations associated with melanoma, which are a result of sun exposure," senior and corresponding author Hunter Shain, a dermatology and cancer researcher at the University of California at San Francisco, said in a statement.

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Bloomberg reports that vaccine developers won't have to conduct large trials of updated vaccines or vaccine boosters aimed at new viral variants.

The SARS-CoV-2 variant uncovered in California may be more transmissible and partially evade vaccine-induced antibody response, the Los Angeles Times reports.

Francis deSouza, the CEO of Illumina, calls for a global SARS-CoV-2 genomics surveillance network, according to the Financial Times.

In PNAS this week: immunotherapy for hard-to-treat breast cancers, effects of oncogenic histone H3K36M mutations, and more.

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