In a departure from initial plans, Harvard Medical School's Personal Genome Project will choose participants for whole-genome sequencing based on their phenotype, according to project organizers.

The PGP, which will enroll 1,000 participants in the so-called PGP-1K cohort this month, said that it plans to make more genome data from current participants publicly available by the end of November, including complete genomes of the first 10 participants, known as the PGP-10, and four additional genomes from "recent enrollees."

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In PLOS this week: Uncovering variants associated with diabetes-related kidney disease, a sequencing study of hepatitis E viruses circulating in Cambodia, and more.

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Sep
17
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This online seminar will provide examples of how commercial and hospital-affiliated clinical labs are successfully developing and deploying high-throughput next-generation sequencing-based testing services for genetic diseases. 

Sep
24
Sponsored by
Personalis

This online seminar will outline a targeted enrichment technology to improve next-generation sequencing assays for cancer research and clinical applications. 

Oct
07
Sponsored by
Personal Genome Diagnostics

This webinar will highlight the key considerations and applications of next-generation sequencing for managing non-small cell lung cancer patients using plasma-based approaches. 

Oct
15
Sponsored by
Parabase

This webinar will discuss the benefits of a rapid targeted next-generation sequencing (TNGS) panel, using dried blood spots, for second-tier newborn metabolic and hearing loss screening and its immediate utility for high-risk diagnostic testing in the neonatal intensive care unit.