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Home » PDL1 Amplifications Mark Subset of Solid Tumors, May Point to Checkpoint Blockade Response

PDL1 Amplifications Mark Subset of Solid Tumors, May Point to Checkpoint Blockade Response

Jun 15, 2018
|
staff reporter

NEW YORK (GenomeWeb) – A subset of solid tumors containing PDL1 amplifications appear more prone to respond to immune checkpoint blockade immunotherapy, even in the absence of high PD-L1 protein expression, microsatellite instability (MSI), or enhanced tumor mutational burden (TMB).

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