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Papers of Note : Mar 29, 2011

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Circumventing heterozygosity: sequencing the amplified genome of a single haploid Drosophila melanogaster embryo.
Langley CH, Crepeau M, Cardeno C, Corbett-Detig R, Stevens K.
Genetics. 2011 Mar 24. [Epub ahead of print]


Highly sensitive pyrosequencing based on the capture of free APS with ATP sulfurylase.
Wu H, Wu W, Chen Z, Wang W, et al.
Anal Chem. 2011 Mar 25. [Epub ahead of print]


Population-based resequencing of experimentally evolved populations reveals the genetic basis of body size variation in Drosophila melanogaster.
Turner TL, Stewart AD, Fields AT, Rice WR, Tarone AM.
PLoS Genet. 2011 Mar;7(3):e1001336.


A next-generation sequencing method for overcoming the multiple gene copy problem in polyploid phylogenetics, applied to Poa grasses.
Griffin PC, Robin C, Hoffmann AA.
BMC Biol. 2011 Mar 23;9(1):19.


Full genome re-sequencing reveals a novel circadian clock mutation in Arabidopsis.
Ashelford K, Eriksson MM, Allen CE, D'Amore L, et al.
Genome Biol. 2011 Mar 23;12(3):R28.


Molecular dynamics simulations of DNA within a nanopore: arginine-phosphate tethering and a binding/sliding mechanism for translocation.
Bond PJ, Guy AT, Heron AJ, Bayley H, Khalid S.
Biochemistry. 2011 Mar 24. [Epub ahead of print]


ExpEdit: a web server to explore human RNA editing in RNA-seq experiments.
Picardi E, Mattia D, Carrabino D, Castrignanò T, Pesole G.
Bioinformatics. 2011 Mar 22. [Epub ahead of print]


Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage.
Bracken CP, Szubert JM, Mercer TR, Dinger ME, et al.
Nucleic Acids Res. 2011 Mar 22. [Epub ahead of print]


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Genome-wide studies reveal that lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells.
Peng S, Chen LL, Lei XX, Yang L, et al.
Stem Cells. 2011 Mar;29(3):496-504. doi: 10.1002/stem.591.


A practical comparison of de novo genome assembly software tools for next-generation sequencing technologies.
Zhang W, Chen J, Yang Y, Tang Y, et al.
PLoS One. 2011 Mar 14;6(3):e17915.


Revealing the genetic structure of a trait by sequencing a population under selection.
Parts L, Cubillos F, Warringer J, Jain K, Salinas F, Bumpstead SJ, Molin M, Zia A, Simpson JT, Quail MA, Moses AM, Louis EJ, et al.
Genome Res. 2011 Mar 21. [Epub ahead of print]


Block copolymer nanoparticles as nanobeads for the polymerase chain reaction.
Zhang S, Prud'homme RK, Link AJ.
Nano Lett. 2011 Mar 21. [Epub ahead of print]


In addition to the above papers, a new volume of Methods in Molecular Biology (Vol. 733) includes a series of methods papers for next-generation sequencing.

The Scan

Booster for At-Risk

The New York Times reports that the US Food and Drug Administration has authorized a third dose of the Pfizer-BioNTech SARS-CoV-2 vaccine for people over 65 or at increased risk.

Preprints OK to Mention Again

Nature News reports the Australian Research Council has changed its new policy and now allows preprints to be cited in grant applications.

Hundreds of Millions More to Share

The US plans to purchase and donate 500 million additional SARS-CoV-2 vaccine doses, according to the Washington Post.

Nature Papers Examine Molecular Program Differences Influencing Neural Cells, Population History of Polynesia

In Nature this week: changes in molecular program during embryonic development leads to different neural cell types, and more.