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Paired Ends: Toby Bloom, Liying Zhang, Michelle Lamendola-Essel

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The New York Genome Center has a number of new hires (see story, this issue).

Toby Bloom is the center's deputy scientific director of informatics. She joins the NYGC from the Broad Institute, where she was director of informatics for the Genome Sequencing Center. She holds a PhD in computer science and engineering from MIT.

Liying Zhang is interim director of the NYGC's CLIA-certified laboratory. Zhang is currently the director of the diagnostic molecular genetics laboratory at Memorial Sloan-Kettering and has a certificate of qualification from New York state in molecular oncology and in molecular genetics. She holds an MD from Peking University and a PhD from Johns Hopkins University.

Michelle Lamendola-Essel, who is also certified by New York state, has been hired as senior clinical laboratory technician and will be responsible for running the CLIA lab on a day-to-day basis. Previously, she was lead molecular scientist at Enzo Biochem, and has also held positions at Acupath Laboratories.

The Scan

Long COVID-19 Susceptibility Clues Contained in Blood Plasma Proteome

A longitudinal study in eBioMedicine found weeks-long blood plasma proteome shifts after SARS-CoV-2 infection, along with proteomic signatures that appeared to coincide with long Covid risk.

Tibetan Study Finds Adaptive Variant Influencing Skin Pigmentation

With a combination of phenotyping and genetic data, researchers document at PNAS a Tibetan-enriched enhancer variant influencing melanin synthesis and ultraviolet light response.

Domestication Linked to Nervous System Genes in Inbred Mouse Strains

Researchers highlighted more than 300 positively selected genes in domesticated mice, including genes linked to nervous system function or behavior in Genome Biology.

ALS Genetic Testing May Be Informative Across Age Ranges, Study Finds

Researchers in the journal Brain identified clinically actionable variants in a significant subset of older ALS patients, prompting them to point to the potential benefits of broader test use.