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Paired Ends: Apr 20, 2010


Alexis Borisy is the founding CEO of Foundation Medicine, a Cambridge, Mass.-based startup that aims to bring comprehensive cancer genome analysis into the clinic and to develop clinical laboratory tests using next-generation sequencing and other technologies. The company recently raised $25 million in a Series A funding round led by Third Rock Ventures.

The firm's academic advisors include Eric Lander, director of the Broad Institute, professor of biology at the Massachusetts Institute of Technology, and professor of systems biology at Harvard Medical School; Todd Golub, director of the Broad Institute's cancer program, an investigator in human cancer genetics at the Dana-Farber Cancer Institute and professor of pediatrics at Harvard Medical School; Levi Garraway, an assistant professor of medicine in the Department of Medical Oncology at Dana-Farber; and Matthew Meyerson, director of the Center for Cancer Genome Discovery at Dana-Farber and a professor of pathology at Harvard Medical School.

The firm's board of directors includes CEO Alexis Borisy; Mark Levin, a partner at investor Third Rock Ventures and former CEO of Millennium Pharmaceuticals; David Schenkein, CEO of Agios Pharmaceuticals and former leader of Genentech’s BioOncology development portfolio; and Robert Tepper, a partner at Third Rock Ventures and former president of research and development at Millennium.

Duncan Whitney has joined Allegro Diagnostics as vice president for research and development. Previously, he held executive-level scientific roles at Exact Sciences, US Genomics, and Progenika. Whitney holds PhD and master's degrees in chemistry from the Massachusetts Institute of Technology and a BS in chemistry from Colby College.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.