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The Genome Analysis Centre in Norwich, UK, recently made several new appointments. Kirsten McLay joined TGAC as sequencing operations manager, overseeing high-throughput sequencing. She comes to the center from the Wellcome Trust Sanger Institute.

Melanie Febrer will lead TGAC's library construction team, joining the center from the John Innes Centre, where she was a postdoctoral researcher.

Mark Alston and Xingdong Bian have joined TGAC's bioinformatics team. Alston, who comes to TGAC from the Institute of Food Research, will be involved in annotating bacterial genomes. Bian will implement, maintain, and help to improve web-based interfaces of internal systems.


Saul Kravitz has joined CLC Bio as head of its North American consulting organization. Previously, he was director of bioinformatics software at the J. Craig Venter Institute. Before that, he was at Celera Genomics, where he helped develop algorithms and software infrastructure for high-throughput protein identification and quantitation from mass spectrometry data, and contributed to the development of Celera's whole-genome shotgun assembler. Kravitz holds MSc and PhD degrees in electrical and computer engineering from Carnegie Mellon University, and a BA in physics from Johns Hopkins University.


The Ontario Genomics Institute has appointed four new members to its board of directors: Paul Lucas, president and CEO of GlaxoSmithkline in Canada; Roderick McInnes, director of research of the Jewish General Hospital Lady Davis Institute for Medical Research; Gregg Szabo, vice president of specialty products at Merck Frosst Canada; and James Tiedje, director of the Center for Microbial Ecology at Michigan State University.


Jack Goldstein, a member of Illumina's board of directors, will not stand for re-election at the company's next annual meeting of stockholders, scheduled for May 12, according to Illumina.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.