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Paired Ends: Oct 18, 2011


DNAnexus has added two new board members: Krishna Yeshwant and Geoff Duyk.

Yeshwant is a partner at Google Ventures, where he has been since its inception. Previously, he helped start an electronic data interchange company that was acquired by Hewlett-Packard. He holds a BS in computer science from Stanford University, an MD from Harvard Medical School, and an MBA from Harvard Business School.

Duyk is a partner and managing director at TPG Biotech. Previously he was president of research and development at Exelixis, and was also one of the founding scientific staff at Millennium Pharmaceuticals. He has also served as an assistant professor at Harvard Medical School and worked on the Human Genome Project. He holds a BA in biology from Wesleyan University and an MD from Case Western Reserve University.

The Institute of Medicine has elected 65 new members and five foreign associates. Among them are Richard Gibbs and Claire Fraser-Liggett.

Gibbs is the director of the Human Genome Sequencing Center at the Baylor College of Medicine, which he helped establish in 1996. He played a key role in the National Institutes of Health's Human Genome Project. Gibbs holds a BS and a PhD in genetics and radiation biology from the University of Melbourne.

Fraser-Liggett is the director of the Institute for Genome Sciences at the University of Maryland. Previously she was president and director of the Institute for Genomic Research in Rockville, Md. She has played a key role in the sequencing and analysis of human, animal, plant, and microbial genomes, and has led teams that sequenced the genomes of several human pathogens. She holds a PhD in pharmacology from the State University of New York at Buffalo.

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.