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Paired Ends: Mar 8, 2011


Daniel Von Hoff, physician-in-chief at the Translational Genomics Research Institute, was presented with the Scripps Genomic Medicine Award last week at the annual Future of Genomic Medicine conference.

In presenting the award, Eric Topol, director of the Scripps Translational Science Institute, cited Von Hoff's "pioneering efforts" in sequencing the genomes of patients with rare cancers in order to determine the best course of treatment.

John Quackenbush of the Dana-Farber Cancer Institute has been awarded a $4 million fellowship by Australia's National Health and Medical Research Council to study chemotherapy-resistant ovarian cancers. He will join Sean Grimmond's team at the University of Queensland's Center for Medical Genomics, the largest genome sequencing facility in Australia.

Quackenbush is a professor of computational biology and bioinformatics at Dana-Farber and has been working on developing better computational methods to interpret sequence data, particularly in cancer. He also participated in the Human Genome Project.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.