PacBio, U Chicago Develop Single-Molecule Hydroxymethylation Sequencing Technique

Dec 06, 2011

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Researchers at the University of Chicago have combined a chemical labeling method for 5-hydroxymethylcytosine with sequencing on the Pacific Biosciences RS, allowing for single-base resolution of the epigenetic marker, which is involved in cell development and may play a role in some human disease.

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