By Julia Karow

This article was originally published Sept. 17.

COLD SPRING HARBOR, NY – Pacific Biosciences has demonstrated that it can use its single-molecule real-time sequencing technology to identify methylated DNA bases, and to directly sequence RNA molecules. It has also applied strobe sequencing, a sequencing mode that generates multiple gapped reads from a single DNA strand, to map complex structural variations in human fosmid DNA.

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NPR reports that researchers in Italy are testing a gene drive aimed at controlling mosquito populations.

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In Genome Biology this week: post-transcriptional modification-based stratification of glioblastoma, single-cell analysis of gene expression and methylation in human iPSCs, and more.

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