NEW YORK (GenomeWeb) — Pacific Biosciences last week announced the release of its latest updated chemistry and software, which the company says increases the performance and output of its RS II sequencing platform by about 45 percent.

The new chemistry, P6-C4, represents the company's sixth generation of polymerase and fourth generation of associated base pairs, reagents, and buffers. It further extends the PacBio RS II's average read length to between 10,000 and 15,000 bases depending on the library used, with the platform's longest reads exceeding 40,000 bases.

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