PacBio-Northeastern Team Demonstrates Increased Loading Efficiency with Combo of Nanopore, Zero-Mode Waveguide | GenomeWeb

NEW YORK (GenomeWeb News) — Researchers at Northeastern University and Pacific Biosciences have developed a method for reversibly drawing molecules into the nanowells of PacBio's chips, thus increasing the efficiency for loading proteins and DNA.

Potentially, the approach could enable PacBio's real-time single-molecule sequencing technology to analyze samples with limiting amounts of DNA, such as epigenetically modified mammalian DNA, and to sequence long DNA fragments more efficiently. It could also allow the company's chips to be reused more easily.

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