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NEW YORK (GenomeWeb) – Karius said today that Nohla Therapeutics will use Karius' next-generation sequencing plasma test for pathogen detection in a randomized trial evaluating Nohla's lead product, a cellular therapy called NLA101, in acute myeloid leukemia patients with chemotherapy-induced neutropenia.

Karius' test uses NGS to detect microbial cell-free DNA in plasma from more than a thousand pathogens from a single blood draw. The test will enable Nohla to easily monitor immunocompromised patients for infections, including from bacteria, DNA viruses, fungi, and protozoa.

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