NEW YORK (GenomeWeb News) – A pair of studies that appeared in The New England Journal of Medicine this week identified a rare variant of the TREM2 gene as a potent risk factor for late-onset Alzheimer's disease.

A number of risk variants for Alzheimer's disease have previously been reported, though many of them have been linked to familial early-onset Alzheimer's disease, while others that have been associated with the late-onset form of the disease have generally been shown to confer low risk, with the notable exception of the ε4 allele of apolipoprotein E.

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The US National Institutes of Health and the Food and Drug Administration have proposed changing gene therapy oversight, the Associated Press reports.

Nature News reports that the Salk Institute has asked for the scope of a gender discrimination lawsuit brought against it to be narrowed.

CNBC reports that the sequencing startup Veritas aims to sequence individuals who fall at extremes.

In PLOS this week: genotyping of indigenous North African goats, program to simulate evolve and resequencing studies, and more.

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