NEW YORK (GenomeWeb News) – A pair of studies that appeared in The New England Journal of Medicine this week identified a rare variant of the TREM2 gene as a potent risk factor for late-onset Alzheimer's disease.

A number of risk variants for Alzheimer's disease have previously been reported, though many of them have been linked to familial early-onset Alzheimer's disease, while others that have been associated with the late-onset form of the disease have generally been shown to confer low risk, with the notable exception of the ε4 allele of apolipoprotein E.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.