By Monica Heger

Researchers have combined serial analysis of gene expression, or SAGE, with high-throughput sequencing to profile gene expression in both normal and cancer samples of human breast tissue. The method, published last week in Genome Research, is similar to RNA-seq but requires less total sequencing, although it also yields less data.

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Technology Review reports that researchers in the US have used CRISPR to modify a number of human embryos.

By introducing genes from butterfly peas and Canterbury bells, researchers in Japan have developed a blue chrysanthemum, according to NPR.

Plant researchers plan to sequence some 10,000 samples that represent the major plant clades, ScienceInsider reports.

In Nature this week: a Danish reference genome, and more.