New Sequencing Approach Examines Specific RNA Epigenetic Modifications

Jul 05, 2016

|

NEW YORK (GenomeWeb) – Researchers from Boston and Los Angeles have devised a new sequencing approach to gauge N⁶-methyladenosine modifications of RNA molecules.

N⁶-methyladenosine (m⁶A) is a reversible chemical modification of mRNAs and long noncoding RNAs. While such modifications have been linked to RNA metabolism, not much is known about how common modified transcripts are and what their regulatory effect is, the researchers noted.

To read the full story....

...and receive Daily News bulletins.

Already have a GenomeWeb or 360Dx account?
Login Now.

Don't have a GenomeWeb or 360Dx account?
Register for Free.

Breaking News

The Scan

Harvard Prof Charged

A Harvard University professor has been charged with making false claims regarding funds he received from China, the New York Times reports.

But What About That Preserved Frog Smell?

Discover magazine reports that animal dissections might dissuade students from science careers, but that a firm has developed synthetic frogs for dissections.

Level of Transparency

Nature News reports that a US panel is reviewing current guidelines for federally funded gain-of-function viral research.

PNAS Papers Describe Amish De Novo Mutation Decrease, RNA Sequencing Method, Precision Med Results

In PNAS this week: de novo mutation patterns among the Amish, an alternative RNA-seq method, and more.

Featured White Papers

Analytical Validation of the QuantideX NGS DNA Hotspot 21 Kit, A Diagnostic NGS System for the Detection of Actionable Mutations in FFPE Tumors

Independent, Third-Party Studies Evaluating the Efficiency of the Twist Human Core Exome Kit for Target Sequencing

The Importance of Coverage Uniformity Over On-Target Rate for Efficient Targeted NGS

KAPA RNA HyperPrep: A Streamlined Library Preparation Workflow that Enables Robust Gene Expression Profiling Using RNA-sequencing

Feb

05

Featured Webinar

Development of a Novel Multiplex Assay: A Partnership Case Study

This webinar will provide a behind-the-scenes look at the collaborative development of a novel multiplex assay to speed detection of mosquito-borne illness in the clinical setting.

Feb

20

Featured Webinar

Advances in NGS Gene Expression Studies to Reduce The Cost of Sequencing

This webinar will discuss the use of 3’ mRNA sequencing to reduce the cost of gene expression studies on Illumina NGS systems.

Feb

25

Featured Webinar

Long-Read Sequencing of Human Transcription Provides Insights into Metastatic Cancer

This webinar will discuss a study that used long-read transcriptome sequencing to explore the distribution of isoforms in colon cancer samples and their metastasis counterparts.

Feb

26

Featured Webinar

Transformation of the Lab to Fight Genetic Illnesses in the Amish and Mennonite Populations

This webinar will explain how the Clinic for Special Children in Strasburg, Pennsylvania, has transformed its DNA workflows to improve the diagnosis and treatment of genetic illnesses that are prevalent in the pediatric population of its community.

Menu

New Sequencing Approach Examines Specific RNA Epigenetic Modifications

To read the full story....

Breaking News

Helix Researchers Analyze Rare Variants in 70,000 Exomes From two Cohorts

Novacyt Posts 4 Percent Drop in Preliminary 2019 Revenues

Saga, Servier Sign Liquid Biopsy Services Deal

Co-Diagnostics Closes $5M Offering of Shares

Predictive Technology Group, Atrin Pharmaceuticals Launch Oncology MDx Collaboration

PerkinElmer Q4 Revenues Rise 7 Percent

The Scan

Harvard Prof Charged

But What About That Preserved Frog Smell?

Level of Transparency

PNAS Papers Describe Amish De Novo Mutation Decrease, RNA Sequencing Method, Precision Med Results

Featured White Papers

Development of a Novel Multiplex Assay: A Partnership Case Study

Advances in NGS Gene Expression Studies to Reduce The Cost of Sequencing

Long-Read Sequencing of Human Transcription Provides Insights into Metastatic Cancer

Transformation of the Lab to Fight Genetic Illnesses in the Amish and Mennonite Populations

What's Popular?

Diagnostics Developers Leap Into Action on Novel Coronavirus Tests

Whole-Genome Sequencing, Deep Phenotyping Shows Many Adults Harbor Pathogenic Genetic Variants

Helix Researchers Analyze Rare Variants in 70,000 Exomes From two Cohorts

CMS to Cover FDA-Approved, -Cleared NGS Germline Tests for Breast, Ovarian Cancer Patients

Lucence Dx Targets Late-Stage Lung Cancer Monitoring With 2020 US Entry

Sponsorships