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New Products: Zymo's Methyl-Seq and 5-hmC Prep Kits; Gene Codes' Sequencher 5.2


Zymo Research Corporation has launched Pico Methyl-Seq Library Prep and RRHP 5-hmC Library Prep kits for next-gen sequencing-based analysis of 5-methylcytosine and 5-hydroxymethylcytosine, respectively. The kits are compatible with next-gen sequencing on Illumina platforms. The Pico Methyl-Seq kit is a modified whole-genome bisulfite sequencing library prep workflow that can be completed in less than six hours, according to the company. The RRHP 5-hmC kit uses a reduced representation hydroxymethylation profiling protocol that requires 100 ng of input DNA, is quantitative and strand-specific.

Gene Codes Corporation has released Sequencher 5.2, the latest release of its DNA sequencing software that can analyze both Sanger sequencing data and next-gen sequencing data. A new addition to the software is Sequencher Connections, which integrates Sequencher with third-party tools.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.