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New Products: WuXi's NextCode Analysis; Dana-Farber's Heme Panel; More

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WuXi PharmaTech's Genome Center is now offering analysis services from NextCode Health, a bioinformatics company in Cambridge, Mass., which will provide population-scale genome analysis. NextCode will work with the WuXi Genome Center to process sequence data from WuXi's customers and produce a report discussing the medical implications.


The Dana-Farber Cancer Institute and the Brigham and Women's Cancer Center have a launched Rapid Heme Panel, a next-gen sequencing-based panel that analyzes alterations in 95 genes that are frequently associated with leukemias and myeloid disorders. The test has a turnaround time of five business days.


Enzymatics has launched Archer Assay Designer, a software platform to design custom primer panels to generate target-enriched libraries in order to identify gene fusions through next-gen sequencing. The software allows the user to search for genes and exons of interest.


Almac Group has launched a CLIA validated next-gen sequencing assay for P53 mutations. The test can be run on formalin-fixed paraffin-embedded samples and covers all coding regions and upstream regulatory regions of P53.


Swift Biosciences has launched an early access program for its next-generation sequencing-based TP53 Panel that covers all coding exons of the gene. The panel uses Swift's Accel-NGS Amplicon Panel technology and runs on Illumina's sequencing instruments. In addition, it is planning another panel using the Accel-NGS Ampliocn technology that will target over 200 clinically relevant cancer mutations.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.