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New Products: Sage Science's PippinHT; MacVector Software Update

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Sage Science has launched PippinHT, a high-throughput DNA sizing platform for next-generation sequencing workflows. The platform incorporates the company’s sizing technology and increases throughput to 24 samples per run, compared to a maximum of five with Pippin Prep or BluePippin, and shortens run times by about 50 percent.


MacVector has launched MacVector 13.5, software for analyzing next-generation sequencing data. The new release includes enhancements to the Align to Reference tool, allowing it to handle circular sequences; and Align to Folder, which can scan NGS datasets with a DNA or protein query.

The Scan

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.

Study Reveals Potential Sex-Specific Role for Noncoding RNA in Depression

A long, noncoding RNA called FEDORA appears to be a sex-specific regulator of major depressive disorder, affecting more women, researchers report in Science Advances.

New mRNA Vaccines Offer Hope for Fighting Malaria

A George Washington University-led team has developed mRNA vaccines for malaria that appear to provide protection in mice, as they report in NPJ Vaccines.

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.