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New Products: PacBio's Base Modification Software; GenBank 190.0

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Pacific Biosciences has launched software to detect DNA base modifications on the PacBio RS. The software is available as a free download from PacBio's DevNet portal and will work on any data generated by the PacBio RS with the C2 chemistry.


GenBank version 190.0 is now available here via FTP from the National Center for Biotechnology Information. It contains data as of June 15.

The new release comprises approximately 141 gigabases of data from 154 million entries of non-whole genome sequencing, non-CON sequences, and around 288 gigabases from 82 million entries from whole-genome sequences. Uncompressed, the release 190.0 flatfiles require around 553 gigabases of sequence files only.

Since the previous release in February, the non-WGS/non-CON portion grew by 2.1 gigabases, increasing the number of entries by 2.3 million. An additional 1.6 million records were updated.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.