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New Products: OGT's RNA-Seq Services; Agilent's SureDesign; and More

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Oxford Gene Technology has launched the Genefficiency RNA Sequencing service. The service is customizable, and includes a consultation with a bioinformatician after the data report is delivered.


Agilent Technologies has introduced SureDesign, an online interface to help researchers create customized target enrichment panels for next-generation sequencing. The interface is compatible with all of Agilent's target-enrichment formats, including the HaloPlex and SureSelect systems.


Researchers from the University of Maryland and the Massachusetts Institute of Technology have released TopHat 2.0.5 and CummeRbund 2.0.0, respectively. The TopHat release, available here, includes new options to control the read alignment
and to improve mapping accuracy, as well as the ability to resume partial runs.

The CummeRbund release, available here, offers new options and features, fixes bugs, and fully supports Cuffdiff2.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.