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New Products: NuGen's Ovation Target Enrichment; HTG Molecular's EdgeSeq Assay

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NuGen has launched its Ovation Target Enrichment System, which uses NuGen's proprietary single primer enrichment technology. The firm has also launched two oncology panels — Ovation Cancer Panel Target Enrichment, which targets over 300 cancer genes, and Ovation Gene Fusion Target Enrichment, which targets over 400 cancer genes that are involved in gene fusions.


HTG Molecular Diagnostics has launched HTG EdgeSeq miRNA Whole Transriptome Assay to analyze the expression of 2,275 microRNAs that are described in the miRBase v20 database. The assay works with formalin-fixed paraffin-embedded tissue samples, is automated on the HTG Edge System and couples HTG Molecular's proprietary nuclease protection chemistry with next-generation sequencing.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.