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New Products: NuGen's Ovation Fusion Panel

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NuGen has launched Ovation Fusion Panel Target Enrichment System, an assay that will detect all possible fusion events involving 446 cancer fusion genes. The assay uses NuGen's proprietary Single Primer Enrichment Technology, a single primer strategy that requires only one partner exon to be targeted, which enables detection of both known and novel fusion events, as well as alternative isoforms, according to the company. It requires 10 ng of total RNA from either fresh frozen or formalin-fixed paraffin-embedded tissue.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.