Skip to main content
Premium Trial:

Request an Annual Quote

New Products: NuGen's InDA-C RNA-seq Method

Premium

NuGen has launched a method for RNA-seq — insert dependent adapator cleavage (InDA-C) — that uses primers during library creation to target specific transcripts for depletion. According to the company, the method is ideal for working with challenging samples, including model organisms. The method is used in NuGen's Ovation Human Blood and FFPE RNA-seq Systems to remove human reticulocyte globin and ribosomal RNA, but the company is now offering to assist researchers as a no-cost design service in choosing InDA-C primers.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.