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New Products: Illumina's V4 HiSeq Reagent Kits

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Illumina has launched its V4 reagent kits for the HiSeq, which can give up to 1 terabase of data per six-day run. According to the company, a single run can sequence 10 genomes, 150 exomes, or 80 whole transcriptomes. The kit is shipping now and requires a software upgrade. The specified performance is available in all HiSeq 2500/1500s built in factory and all HiSeq 2000s shipped in 2013.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.