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New Products: Illumina's V4 HiSeq Reagent Kits

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Illumina has launched its V4 reagent kits for the HiSeq, which can give up to 1 terabase of data per six-day run. According to the company, a single run can sequence 10 genomes, 150 exomes, or 80 whole transcriptomes. The kit is shipping now and requires a software upgrade. The specified performance is available in all HiSeq 2500/1500s built in factory and all HiSeq 2000s shipped in 2013.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.