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New Products: Illumina's Nextera Exome Kits; BGI's PDXomics

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Illumina has launched its Nextera Exome and Custom Enrichment Kits for sample preparation for next-gen sequencing. The kits require 50 nanograms of starting DNA. The exome kit targets more than 62 megabases of coding regions and untranslated regions, and provides 12-plex pre-enrichment sample pooling.


BGI has developed PDXomics, a filtering tool for cancer sequence data to classify reads of a tumor xenograft from reads from the host. According to BGI, the tool can be used to develop patient-derived xenografts.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.