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New Products: Illumina's MiSeqDx Universal Kit; AC-Gen Reading Life's HC-Gen Test

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Illumina has applied the CE mark to its MiSeqDx system and MiSeqDx Universal Kit, enabling laboratories enabling laboratories to develop in vitro diagnostic tests on the MiSeqDx. The system and kit now conform to the IVD Directive. The MiSeqDx Universal Kit includes the library preparation reagents, sample index primers, and sequencing consumables needed for laboratories to develop amplicon assays. The new functionality of the system and the new kit will begin shipping in Europe in November. Illumina received a CE mark for its two cystic fibrosis assays on the MiSeqDx system in July (CSN 7/3/2013).


AC-Gen Reading Life, a Spanish biotech company, has launched its HC-Gen test, a next-generation sequencing based hereditary cancer test. The assay analyzes 37 genes and 89 SNPs that confer a predisposition to breast, ovarian, colon, or pancreatic cancers.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.