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New Products: Fluidigm's C1 DNA Sequencing Workflow

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Fluidigm has launched C1 DNA Sequencing, a sample prep workflow for single-cell sequencing that runs on its C1 Single-Cell Auto Prep System (see article in this week's issue). The workflow is designed for targeted, exome, or whole-genome sequencing of single cells in heterogeneous cell populations and enables researchers to detect somatic mutations, such as SNPs, small indels, and translocations.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.