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New Products: FlexGen's FleXelect kits; Hamilton Robotics' automated sample prep kit; Galaxy update

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FlexGen has launched a set of target enrichment products in its FleXelect product line. The products include a whole-exome enrichment kit as well as several targeted gene panels, including a cancer risk panel, hereditary diseases panel, and a BRCA screening kit.


Hamilton Robotics has launched its automated sample prep enrichment solution, which is based on its Microlab Starlet Liquid Handling Workstation, for sequencing on Roche's 454 GS FLX. The workflow integrates Roche's REM e liquid handling system to enrich up to eight samples. Additionally, the protocol automates five hours of manual work and results in less variability and more consistent results, according to the company.


Researchers at Pennsylvania State University and Emory University have released a new version of Galaxy. The new version now supports TopHat 1.4.0 and Cufflinks, CuffDiff, and CuffCompare 1.3.0 as well as Python, Sam Tools, FASTQC, and Picard.

The tool also enables sharing of workflows and includes a direct link to browse VCF and BAM files in the Integrative Genomics Viewer as well as new visualization features, performance upgrades, and drag-and-drop composite track creation.


Researchers at the Massachusetts Institute of Technology and Harvard University have released CummeRbund 1.1.1, software for analyzing Cufflinks RNA-seq output. The new release, available here, fixes a number of bugs and includes new features. The new version will also be available as part of the Bioconductor development version 2.10.


The National Center for Biotechnology Information has added new attributes to entries in its refSNP database including: clinical significance, minor allele frequency and global minor allele frequency, suspect variations, and allele origin. Clinical significance scores are provided by submitters and not interpreted by the NCBI. The attributions are in the ASN1_flat files, available here via FTP server.

The Scan

Call for a Different Tack

Experts weigh the value of recent experiments testing genetically modified pig kidneys using brain-dead individuals, according to Nature News.

Wastewater Warning

The New York Times reports that wastewater surveillance in some parts of the US point to a possible surge.

Can't Get in the Program

Due to the Northern Ireland protocol dispute, the European Union is preventing UK researchers from joining the Horizon Europe research program, the Times of London reports.

Science Paper on Spatial-Controlled Genome Editing

In Science this week: approach to enable a CRISPR-Cas13a-based system to be used as a cancer therapy.