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New Products: Cofactor Genomics' Bovine Exome Capture Kit; GIS's Opera; Bowtie Updated

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Cofactor Genomics has launched a bovine exome capture kit that will target 46 megabases of the cow genome. The company collaborated with scientists from the US Department of Agriculture to develop the kit, which is based on the Bos taurus assembly from the Center for Bioinformatics and Computational Biology at the University of Maryland.


The Genome Institute of Singapore has launched Opera, a sequence assembly program for paired-end reads. The algorithm is available for free download here. According to the researchers, the algorithm also comes with a quality guarantee and scales to large datasets.


Johns Hopkins Bloomberg School of Public Health has released Bowtie 2.0.0 beta 4, available here. The updated version of the sequence aligning tool contains accuracy improvements and includes fixes for several bugs.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.