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New Products: CellMiner; BGI's PDXomics

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The National Institutes of Health has updated its CellMiner software, available on the National Cancer Institute's website. CellMiner enables researchers and physicians to query data from 22,379 genes catalogued in the NCI-60 database and from 20,503 previously analyzed chemical compounds, including 102 US Food and Drug Administration-approved drugs. The software allows researchers to compare patterns of drug activity and gene expression to each other and also to patterns of interest. The software can also calculate correlations between genes and drug activity profiles and identify statistically significant correlations.


BGI has developed PDXomics, a filtering tool for cancer sequence data to classify reads of a tumor xenograft from reads from the host. According to BGI, the tool can be used to develop patient-derived xenografts.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.