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New Products: Appistry's CGA Suite; PacBio's SMRT Analysis v2.1; IDT's Blocking Oligos

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Appistry has expanded its Cancer Genome Analysis Suite to include additional tools developed by the Broad Institute for analyzing next-generation sequencing data. A tool for estimating cross-contamination in NGS tumor/normal samples called ContEst has been added to the CGA Suite.


Pacific Biosciences has released updated software, SMRT Analysis v2.1. New features include 10- to 20 times faster and better quality microbial genome assemblies using HGAP 2.0, enhanced bar coding support, consensus calling on diploid samples, BridgeMapper visualization tool for assembly Q/C analysis, support for analysis of data generated using the latest P5C3 chemistry, and more.


Integrated DNA Technologies has launched xGen Universal Blocking Oligos. The oligos help to decrease complexity and increase throughput of target capture experiments for next-generation sequencing without degradation of performance.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.