Ambry Genetics has launched four targeted sequencing-based cancer panels: CancerNext, BreastNext, ColoNext, and OvaNext.

The CancerNext panel targets and sequences 23 genes that contribute to increased risk for breast, colon, ovarian, uterine, and other cancers. It excludes the BRCA1 and BRCA2 genes. The test sequences the coding regions of all 23 genes, plus at least 20 bases into the 5' and 3' ends of the introns. Gross deletions and duplications are analyzed for 19 of the genes.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.