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New Products: Dec 21, 2010


SoftGenetics has released its latest version of Mutation Surveyor software, which is compatible with all major capillary electrophoresis sequencing systems. The new release includes improvements to two of the company's algorithms to reduce false positive mutation calls in regions of poor dye mobility, and to complete alignment more quickly and effectively, according to the company.

The software also now includes a contig assembly function, as well as a function that recognizes "dye blobs," and will not call them as possible variants.

release 181.0 is available here via FTP from the National Center for Biotechnology Information. It contains data as of Dec. 14. The new release comprises approximately 122 gigabases and 130 million entries from non-WGS, non-CON sequences, and 177 gigabases and 59.6 million entries from WGS sequences.

Uncompressed, release 181.0 flat files require roughly 468 gigabytes for sequence files only. The ASN.1 data require approximately 384 gigabytes.

The Scan

Push Toward Approval

The Wall Street Journal reports the US Food and Drug Administration is under pressure to grant full approval to SARS-CoV-2 vaccines.

Deer Exposure

About 40 percent of deer in a handful of US states carry antibodies to SARS-CoV-2, according to Nature News.

Millions But Not Enough

NPR reports the US is set to send 110 million SARS-CoV-2 vaccine doses abroad, but that billions are needed.

PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps

In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more.