SoftGenetics has released its latest version of Mutation Surveyor software, which is compatible with all major capillary electrophoresis sequencing systems. The new release includes improvements to two of the company's algorithms to reduce false positive mutation calls in regions of poor dye mobility, and to complete alignment more quickly and effectively, according to the company.
The software also now includes a contig assembly function, as well as a function that recognizes "dye blobs," and will not call them as possible variants.
GenBank release 181.0 is available here via FTP from the National Center for Biotechnology Information. It contains data as of Dec. 14. The new release comprises approximately 122 gigabases and 130 million entries from non-WGS, non-CON sequences, and 177 gigabases and 59.6 million entries from WGS sequences.
Uncompressed, release 181.0 flat files require roughly 468 gigabytes for sequence files only. The ASN.1 data require approximately 384 gigabytes.