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New Products: Dec 7, 2010

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Olink Genomics has released six gene panel kits from its Selector Technology line for targeted resequencing.

The new kits enrich the coding regions for genes involved in cell signaling pathways. According to the company, the technology allows multiplex amplification of thousands of genomic fragments in one tube, and provides close to 100 percent specificity on target alignment, which makes it suitable for clinical applications. Additionally, the kits are compatible with all next-generation sequencing platforms.


Integromics has launched its next-generation sequencing functional bioinformatics analysis software SeqSolve. According to the company, the first version of the software features a broad RNA-seq analysis portfolio including gene expression measurement and interactive scientific visualizations and does not require bioinformatics expertise.


The Wellcome Trust Sanger Institute has released version 50 of COSMIC, the Catalogue of Somatic Mutations in Cancer. The new version includes a full genome browser, GMOD GBrowse, which has been linked into the COSMIC websystem in order to make genomic coordinates available, including coding and non-coding mutations, gene footprints, structural rearrangements, and copy number variants.

In addition, the new version includes genome-wide examinations of 24 additional tumors, comprising rearrangement screens of 17 pancreatic tumors and full exome analyses of 7 renal tumors. Additionally, two new curated cancer genes have been added — ARID1A, which has been identified as a tumor suppressor gene, and PPP2R1A, which has been identified as an oncogene.



Epigentek
has released its EpiSonic Multi-Functional Bioprocessor 1000, a sonication system used for high-throughput sample prep in next generation ChIP and DNA sequencing. The system is digital, and according to the company allows for rapid processing in 96- or 384-well microplates or laboratory tubes between .2 and 15 milliliters.

The system can also be combined with the company's ChromaFlash One-Step ChIP kit to simultaneously process chromatin shearing and immunoprecipitation, and can complete the entire ChIP process in less than one hour, according to Epigentek.


The Scan

Push Toward Approval

The Wall Street Journal reports the US Food and Drug Administration is under pressure to grant full approval to SARS-CoV-2 vaccines.

Deer Exposure

About 40 percent of deer in a handful of US states carry antibodies to SARS-CoV-2, according to Nature News.

Millions But Not Enough

NPR reports the US is set to send 110 million SARS-CoV-2 vaccine doses abroad, but that billions are needed.

PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps

In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more.