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New Products: Nov 16, 2010

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IntergenX has launched its Apollo 324 system for automated DNA library preparation. According to the company, the robotic workstation can prepare eight libraries in about 3.5 hours and up to 24 libraries in one day. It has an 8-tip pipette head with adjustable magnets and two Peltier heating/cooling units for PCR type plates.

The system uses IntergenX's BeadX In-Tip magnetic bead capture system to isolate and purify nucleic acids and to automate end-repair, A-tail addition, adapter ligation and size selection. In addition, the company's PrepX reagent kits are available for the Illumina Genome Analyzer and HiSeq 2000 systems.


The Scan

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.

Study Explores Animated Digital Message Approach to Communicate Genetic Test Results to Family Members

In the Journal of Genetic Counseling, the approach showed promise in participants presented with a hypothetical scenario related to a familial hereditary breast and ovarian cancer syndrome diagnosis.

Computational Tool Predicts Mammalian Messenger RNA Degradation Rates

A tool called Saluki, trained with mouse and human messenger RNA data, appears to improve mRNA half-life predictions by taking RNA and genetic features into account, a Genome Biology paper reports.

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.