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Illumina has released its TruSeq Exome Enrichment Kit (see story, this issue), and its TruSeq sample-prep kit for DNA, RNA, and small RNA applications.

According to the company, the sample-prep kits have optimized adapter design, enable multiplexing and pooling, and provide coverage of greater than 62 megabases of the human exome for less than $300 per sample. Illumina said that the DNA, RNA, and small RNA sample-prep kits can reduce the price of sample enrichment for single-end, paired-end, and multiplexed sequencing by up to 80 percent. In addition, the small RNA kit allows researchers to combine up to 48 samples in one sequencing lane, according to the company.


The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.