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Roche NimbleGen has selected Ambry Genetics as its first certified service provider for the NimbleGenSeqCap EZ Exome workflow. Ambry will provide target-enrichment services using NimbleGen SeqCap EZ Human Exome to capture all human coding sequence, coupled with next-generation sequencing services for genetic research.



New England Biolabs
has introduced a new line of reagents for sample prep — NEBNext mRNA Sample Prep Reagent Set 1 and Master Mix Set 1.

The new products include enzymes, buffers, and protocols to convert mRNA to DNA, and to then construct the library. The reagents are compatible with non-directional mRNA library prep on the Illumina platforms, and also for the preparation of expression libraries.


Researchers at Johns Hopkins School of Public Health have released Myrna, a cloud computing tool for calculating gene expression in large RNA-seq data sets. Myrna uses Bowtie for short-read alignment, and is similar to another cloud-scale genotyping tool, Crossbow.

The Scan

Follow-Up Data Requests to Biobank Participants Ineffective, Study Finds

An effort to recontact biobank enrollees for additional information reports low participation in a new BMJ Open study.

Study Finds Widespread Transmission of Resistant Bacteria in Vietnam Hospitals

A sequencing study in The Lancet Microbe finds widespread transmission of drug-resistant Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii in two Vietnam ICUs.

Novel Brain Cell Organoids Show Promise for Autism Research

University of Utah researchers report in Nature Communications on their development of brain cell organoids to study SHANK3-related autism.

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.